{"product_id":"hpa-axis-lf-90s-pe","title":"HPA Axis LF - 90 caps (PE)","description":"\u003cul\u003e\n\u003cli\u003eServing Size: 2 Capsules\u003c\/li\u003e\n\u003cli\u003eServings Per Container: 45\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch6\u003eActive Ingredients\u003c\/h6\u003e\n\u003cul\u003e\n\u003cli\u003eManganese (as manganese citrate), 10 mg, 435%\u003c\/li\u003e\n\u003cli\u003eAshwagandha (root) extract (Withania somnifera), 500 mg **\u003c\/li\u003e\n\u003cli\u003eN-acetyl-L-tyrosine, 500 mg **\u003c\/li\u003e\n\u003cli\u003ePituitary (anterior) Tissue lyophilized (bovine), 200 mg **\u003c\/li\u003e\n\u003cli\u003eRhodiola rosea 5:1 (root)extract, 100 mg **\u003c\/li\u003e\n\u003cli\u003eAdrenal tissue lyophilized (bovine), 40 mg **\u003c\/li\u003e\n\u003cli\u003eHypothalamus tissue lyophilized (bovine), 40 mg **\u003c\/li\u003e\n\u003cli\u003ePercent Daily Value (DV) not established\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch6\u003eOther Ingredients\u003c\/h6\u003e\n\u003cp\u003eHypromellose (capsule), vegetable stearate, silica.\u003c\/p\u003e\n\u003ch6\u003eUsage Direction\u003c\/h6\u003e\n\u003cp\u003e2 Capsules daily or as direct by a health care practitioner.\u003c\/p\u003e\n\u003cp\u003eHPA Axis LF has been designed to nutritionally support the specific pathways and components, which are a significant\u003cspan\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/physicaenergetics.com\/design-factors\"\u003eCausal Chain\u003c\/a\u003e\u003cspan\u003e \u003c\/span\u003eAdaptogenic Cascade Design in and of themselves.*\u003c\/p\u003e\n\u003cdiv class=\"ewa-rteLine\"\u003e\n\u003cdiv class=\"ewa-rteLine\"\u003eThe hypothalamic, pituitary, adrenal (HPA) axis is the central stress response system. The HPA axis has been accurately described as a dynamic inter-weaving dance between the central nervous and endocrine systems. In fact, you may also refer to it as the ultimate hormonal adaptogenic cascade.\u003c\/div\u003e\n\u003cdiv class=\"ewa-rteLine\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"ewa-rteLine\"\u003eAs such, the HPA axis is responsible for the central adaptation component of the stress response, regulated by a complex system of negative feedback loop mechanisms.\u003c\/div\u003e\n\u003cdiv class=\"ewa-rteLine\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"ewa-rteLine\"\u003eWith repeated exposure to stressors, including pathogens, physical and emotional trauma, and environmental triggers, the body, mind, and heart may begin to entrain with these stressors, creating repeated and sustained HPA axis activation.\u003c\/div\u003e\n\u003cdiv class=\"ewa-rteLine\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"ewa-rteLine\"\u003eEmotionally charged events or trauma early or even later in life may significantly impact the coordination of the HPA axis and the patterns of the body’s stress reaction and response.\u003c\/div\u003e\n\u003cdiv class=\"ewa-rteLine\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"ewa-rteLine\"\u003eUnder conditions of normal exposure to cortisol, tissues only experience glimpses of alarm catecholamines and cortisol. However, with repeated exposure to stress, the sensitized HPA axis may continue to hyper-secrete cortico-releasing hormone (CRH) from the hypothalamus. Over time, CRH receptors in the anterior pituitary will become down-regulated and can produce depression and anxiety symptoms.\u003c\/div\u003e\n\u003cdiv class=\"ewa-rteLine\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"ewa-rteLine\"\u003eIt is vital to support healthy cortisol levels to ensure the hypothalamus and pituitary glands maintain the appropriate level of sensitivity to the negative feedback of cortisol.\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Physica Energetics (Aperture)","offers":[{"title":"Default Title","offer_id":48077364068590,"sku":null,"price":48.4,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0785\/1248\/8686\/files\/HPA-Axis-LF-web-optimized__81508.jpg?v=1782323716","url":"https:\/\/thrivewellnessonline.com\/products\/hpa-axis-lf-90s-pe","provider":"Thrive Worldwide Wellness","version":"1.0","type":"link"}